CCCP
Cat.No:IC2490 Solarbio
CAS:555-60-2
Molecular Formula:C9H5ClN4
Molecular Weight:204.62
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Yellow to brown Solid
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CCCPCAS:555-60-2
Molecular Formula:C9H5ClN4
Molecular Weight:204.62
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Yellow to brown Solid
Qty:
Size:
CAS | 555-60-2 |
Name | CCCP |
Molecular Formula | C9H5ClN4 |
Molecular Weight | 204.62 |
Solubility | Soluble in DMSO ≥100mg/mL |
Purity | ≥98% |
Appearance | Yellow to brown Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 209-103-7 |
MDL | MFCD00001848 |
SMILES | N#C/C(C#N)=N/NC1=CC=CC(Cl)=C1 |
InChIKey | UGTJLJZQQFGTJD-UHFFFAOYSA-N |
InChI | InChI=1S/C9H5ClN4/c10-7-2-1-3-8(4-7)13-14-9(5-11)6-12/h1-4,13H |
PubChem CID | 2603 |
Background | CCCP is an oxidative phosphorylation uncoupler. |
Biological Activity | CCCP是氧化磷酸化解偶联剂,是线粒体质子载体解偶联剂,可增加线粒体膜对质子的通透性,从而破坏线粒体膜电位。[1-3] |
Data Literature Source | [1]. Kwon D,et al. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) suppresses STING-mediated DNA sensing pathway through inducing mitochondrial fission. Biochem Biophys Res Commun. 2017 Aug 30. pii: S0006-291X(17)31704-7. [2]. Sinha D,et al. Synergistic efficacy of Bisbenzimidazole and Carbonyl Cyanide 3-Chlorophenylhydrazonecombination against MDR bacterial strains. Sci Rep. 2017 Mar 17;7:44419. [3]. Kawamoto A,et al. Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure. PLoS One. 2015 Jan 16;10(1):e0117091. |
Unit | Bottle |
Specification | 10mg 25mg 50mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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