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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > 2-Aminoethyl DiphenylborinateCAS：524-95-8
Molecular Formula：C14H16BNO
Molecular Weight：225.09
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 524-95-8 |
| Name | 2-Aminoethyl Diphenylborinate |
| Molecular Formula | C14H16BNO |
| Molecular Weight | 225.09 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS:208-366-5 |
| MDL | MFCD00014823 |
| SMILES | B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN |
| InChIKey | BLZVCIGGICSWIG-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2 |
| PubChem CID | 1598 |
| Target Point | IP3R;Calcium Channel;TRP Channel |
| Passage | Membrane Transporter&Ion Channel;Neuronal Signaling |
| Background | 2-Aminoethyl Diphenylborinate is a cell-permeable IP3R inhibitor, inhibits store-operated Ca2+ (SOC) channels, and activates some TRP channels (V1, V2, and V3). |
| Biological Activity | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1， V2 and V3)[1-3]. |
| Data Literature Source | [1]. Ma S，et al. Effect of Wilforine on the Calcium Signaling Pathway in Mythimna separata Walker MyocytesUsing the Calcium Imaging Technique. J Agric Food Chem. 2019 Nov 27. [2]. Boyac MG，et al. Effects of 2-Aminoethyl Diphenylborinate，a Modulator of Transient Receptor Potential and OraiChannels in Subarachnoid Hemorrhage: An Experimental Study. [3]. Takahashi K，et al. Molecular mechanism of 2-APB-induced Ca2 influx in external acidification in PC12. Exp Cell Res. 2014 May 1;323(2):337-45. |
| Unit | Bottle |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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