Amyloid β-Protein (1-14)
Cat.No:CLP0196 Solarbio
CAS:186319-74-4
Molecular Formula:C73H99N23O25
Molecular Weight:1698.73
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
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My CartCAS:186319-74-4
Molecular Formula:C73H99N23O25
Molecular Weight:1698.73
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
Qty:
Size:
Product Type | Peptides |
CAS | 186319-74-4 |
Sequence(1LC) | DAEFRHDSGYEVHH |
Sequence(3LC) | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His |
Molecular Formula | C73H99N23O25 |
Molecular Weight | 1698.73 |
Purity | ≥95% |
Appearance | Lyophilized powder |
Salt Form | Trifluoroacetate salt |
Source | Synthetic |
Storage | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
Category/Label | Amyloid Peptides |
Background | The N-terminal Aβ fragments Aβ1-14, Aβ1-15, and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The presence of these small peptides is consistent with a catabolic amyloid precursor protein cleavage pathway by β-followed by α-secretase. It has been shown that Aβ1-14, Aβ1-15, and Aβ1-16 increase dose-dependently in response to γ-secretase inhibitor treatment while Aβ1-42 levels are unchanged. |
Reference | [1] E.Portelius et al., Neurodegener. Dis., 10, 138 (2012); [2]E.Portelius et al., Curr. Pharm. Des., 17, 2594 (2011); [3]E.Portelius et al., Alzheimer Res. Ther., 2, 7 (2010). |
Unit | Bottle |
Specification | 1mg 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
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