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My CartMolecular Formula：C113H191N37O34S1
Molecular Weight：2644.05
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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Size：
| Product Type | Peptides |
| Sequence(1LC) | VKRMKESRLEDTQKHRVDFLQ |
| Sequence(3LC) | Val-Lys-Arg-Met-Lys-Glu-Ser-Arg-Leu-Glu-Asp-Thr-Gln-Lys-His-Arg-Val-Asp-Phe-Leu-Gln |
| Molecular Formula | C113H191N37O34S1 |
| Molecular Weight | 2644.05 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Other Peptides |
| Background | This 21-amino acid peptide corresponds to residues 253-273 of human cytochrome P450 CYP3A4. Cytochrome P450, a family of over a thousand different members, is involved the metabolism of a wide variety of both endogenous and foreign compounds, in drug and toxin removal. In insects, xenobiotic metabolism is known to involve members of the CYP6 family of cytochrome P450s. Cytochromes P450 are thought to facilitate tumor invasion and metastasis by the generation of reactive oxygen species during various metabolic steps and by the activation of protein kinases, cellular proteoglycan changes, and lysosomal enzymes. High cytochrome P450 CYP3A4/5 expression may predict metastasis and poor prognosis in osteosarcomas. Its use as a biomarker of therapeutic response will have implications for the treatment of these tumors. |
| Reference | [1] Wang, RW. and AYH. Lu, Drug Metab Dispos. 25, 762 (1997); [2] Dhaini, H. et al. J. Clin. Oncol. 21, 2481 (2003); [3] Danielson, P. et al. Proc. Natl. Acad. Sci. USA 94, 10797 (1997). |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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