VEGFR2/KDR Antagonist
Cat.No:CLP0780 Solarbio
CAS:272121-15-0
Molecular Formula:C40H61N11O9
Molecular Weight:839.99
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
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My CartCAS:272121-15-0
Molecular Formula:C40H61N11O9
Molecular Weight:839.99
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
Qty:
Size:
Product Type | Peptides |
CAS | 272121-15-0 |
Sequence(1LC) | ATWLPPR |
Sequence(3LC) | Ala-Thr-Trp-Leu-Pro-Pro-Arg |
Molecular Formula | C40H61N11O9 |
Molecular Weight | 839.99 |
Purity | ≥95% |
Appearance | Lyophilized powder |
Solubility | DMSO:100 mg/mL; *Ultrasonic solubilization; |
Salt Form | Trifluoroacetate salt |
Source | Synthetic |
Storage | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
Category/Label | Other Peptides |
Background | This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo. |
Reference | [1] Renno, R. et al. Invest. Ophthalmol. Vis. Sci. 43, 3977 (2002); [2] Brekken, R. et al. Cancer Res. 60, 5117 (2000); [3] Jia, H. et al. J. Biol. Chem. 279, 36148 (2004); [4] Ye, F. Gynecol. Oncol. 94, 125 (2004); [5] Binetruy-Tournaire, R. et al. EMBO J. 19, 1525 (2000). |
Unit | Bottle |
Specification | 1mg 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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