Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > Clofibrate

Clofibrate

Manual Download

Cat.No：IC2890 Solarbio

CAS：637-07-0

Molecular Formula：C₁₂H₁₅ClO₃

Molecular Weight：242.7

Storage：Store at 2-8℃，2 years

Purity：≥98%

Appearance：Liquid

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	637-07-0
Name	Clofibrate
Molecular Formula	C₁₂H₁₅ClO₃
Molecular Weight	242.7
Solubility	Soluble in DMSO ≥1mg/mL(Need ultrasonic)
Purity	≥98%
Appearance	Liquid
Storage	Store at 2-8℃，2 years
Density	1.14g/mL
EC	EINECS 211-277-4
MDL	MFCD00000615
SMILES	CC(C)(OC1=CC=C(Cl)C=C1)C(OCC)=O
InChIKey	KNHUKKLJHYUCFP-UHFFFAOYSA-N
InChI	InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3
PubChem CID	2796
Target Point	PPAR
Passage	Cell Cycle;DNA Damage/DNA Repair;Metabolic Enzyme&Protease
Background	Clofibrate is a PPAR agonist.
Biological Activity	Clofibrate is an agonist of PPAR， with EC50s of 50 μM，～500 μM for murine PPARα and PPARγ， and 55 μM，～500 μM for human PPARα and PPARγ， respectively.[1-3]
Data Literature Source	[1]. Willson TM， et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50. [2]. Chen Y， et al. Clofibrate Attenuates ROS Production by Lipid Overload in Cultured Rat Hepatoma Cells. J Pharm Pharm Sci. 2017;20(0):239-251. [3]. Chen SH， et al. Prenatal PPARα activation by clofibrate increases subcutaneous fat browning in male C57BL/6J mice fed a high-fat diet during adulthood. PLoS One. 2017 Nov 2;12(11):e0187507.
Unit	Bottle
Specification	100mg 200mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

Experimental Images

Technical Q&A

Q&A （Total 0 User Q&A）

There is not question and answer now, come and send an inquiry please.

My question

Rank：

My question：

Identifying code：
captcha