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My Cart> Antibodies > Primary Antibodies > Anti-phospho-STAT3 (Tyr705) Polyclonal AntibodyReactivity：Chicken,Rat,Mouse,Human
Application：IHC,ELISA,FCM,IF,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：6774
Host：Rabbit
Qty：
Size：
| Name | Anti-phospho-STAT3 (Tyr705) Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Dog;Pig;Cow;Rabbit;Sheep;Guinea Pig |
| Dilution Ratio | WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg /test. IF 1:100-500. |
| Target | phospho-STAT3 (Tyr705) |
| Background | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Swiss Prot | P40763 |
| Gene ID | 6774 |
| Subcellular Location | Nucleus Cytoplasm |
| Immunogen | A synthetic peptide of human STAT3 around the phosphorylation site of Tyr705: AP(p-Y)LK |
| Calculated MW | 85kDa |
| Observed MW | 84kDa |
| Purification Method | Affinity purification |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Chicken Rat Mouse Human |
| Application | ELISA FCM IF IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with phospho-STAT3 (Tyr705) antibody diluted at 1:1000;Lane: Mouse Heart Mouse Kidney Rat Aorta.
Immunohistochemistry of paraffin-embedded rat pancreas with phospho-STAT3 (Tyr705) antibody diluted at 1:200.
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