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My CartReactivity：Human,Mouse
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：81790
Host：Rabbit
Qty：
Size：
| Name | Anti-RNF170 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Cow;Xenopus laevis;Xenopus tropicalis |
| Dilution Ratio | WB 1:2000-5000. IHC 1:25-100. |
| Target | RNF170 |
| Background | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. |
| Swiss Prot | Q96K19 |
| Gene ID | 81790 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthetic peptide of human RNF170 |
| Public Immunogen Range | 150-200/258aa |
| Calculated MW | 13/19/20/22/27/30kDa |
| Observed MW | 22kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with RNF170 antibody diluted at 1:3000;Lane: HEL,A431.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with RNF170 antibody diluted at 1:50.
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