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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：55255
Application：Blocking Peptide of K113560P Antibody
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| Name | WDR41 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q9HAD4 |
| Gene ID | 55255 |
| Interval Range | 340-390/459aa |
| Background | Non-catalytic component of the C9orf72-SMCR8 complex， a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190， PubMed:27103069， PubMed:27617292， PubMed:28195531).The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP， converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form， thereby promoting autophagosome maturation (PubMed:27103069).As part of the C9orf72-SMCR8 complex， stimulates RAB8A and RAB11A GTPase activity in vitro， however WDR42 is shown not be an essential complex component for this function (PubMed:32303654).The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ULK1/ATG1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069， PubMed:27617292). |
| Application | Blocking Peptide of K113560P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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