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My CartReactivity：Mouse,Rat,Human
Application：IF,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：5771
Host：Rabbit
Qty：
Size：
| Name | Anti-PTPN2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-1000. IF 1:50-200. |
| Target | PTPN2 |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. |
| Swiss Prot | P17706 |
| Gene ID | 5771 |
| Subcellular Location | Cell membrane Cytoplasm Endoplasmic reticulum Endoplasmic reticulum-Golgi intermediate compartment Nucleus |
| Immunogen | Recombinant protein of human PTPN2 |
| Public Immunogen Range | 1-353aa |
| Calculated MW | 48kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Rat Human |
| Application | IF WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunofluorescence analysis of MCF7 cell using PTPN2 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with PTPN2 antibody diluted at 1:1000;Lane: HeLa cells.
Immunofluorescence analysis of A549 cells using PTPN2 antibody diluted at 1:100.
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