Gene Name |
GNB3 |
Synonyms |
CSNB1H;G protein subunit beta 3 |
English Name |
Recombinant human GNB3 protein |
Full Name |
guanine nucleotide binding protein (G protein),beta polypeptide 3 |
Chinese Name |
鸟嘌呤核苷酸结合蛋白(G蛋白)亚基β3 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
P16520 |
Gene ID |
2784 |
Reactivity |
Human Mouse Rat (Dog) |
Molecular Weight |
37kDa |
Interval Range |
1-340aa |
Background |
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit.These subunits are encoded by families of related genes.This gene encodes a beta subunit which belongs to the WD repeat G protein beta family.Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity.This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites.Alternative splicing results in multiple transcript variants.Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |