Gene Name |
YTHDF2 |
Synonyms |
CLL associated antigen KW 14,HGRG8,NY REN 2,YTH domain family protein 2,YTH domain family,member 2,YTHDF2 |
English Name |
Recombinant human YTHDF2 protein |
Full Name |
YTH domain family,member 2 |
Chinese Name |
YTH结构域家族成员2 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q9Y5A9 |
Gene ID |
51441 |
Reactivity |
Human Mouse (2 Zebrafish Monkey) |
Molecular Weight |
39kDa |
Interval Range |
230-579aa |
Background |
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain.The YTH domain is typical for the eukaryotes and is particularly abundant in plants.The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA.In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction.An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity.In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia.This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
No activity experimental data, to be verified. |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |