Gene Name |
CLPTM1 |
Synonyms |
CLPTM1;CLPTM1,transmembrane protein |
English Name |
Recombinant human CLPTM1 protein |
Full Name |
cleft lip and palate associated transmembrane protein 1 |
Chinese Name |
唇裂和腭裂相关跨膜蛋白1 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
O96005 |
Gene ID |
1209 |
Reactivity |
Human Mouse (Bovine Zebrafish Chicken Gorilla) |
Molecular Weight |
40kDa |
Interval Range |
1-350aa |
Background |
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17.Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide.This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils.It causes the release of histamine from basophils and activates eosinophils.This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells.It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.Alternative splicing results in multiple transcript variants that encode different isoforms |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |