Gene Name |
RHBDD1 |
Synonyms |
RHBDD1;RRP4;rhomboid-related protein 4 |
English Name |
Recombinant human RHBDD1 protein |
Full Name |
rhomboid domain containing 1 |
Chinese Name |
rhomboid相关蛋白4 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q8TEB9 |
Gene ID |
84236 |
Reactivity |
Human Mouse Rat (Gorilla) |
Molecular Weight |
12kDa |
Interval Range |
1-106aa |
Background |
Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions.Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins.Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins.Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing.Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway.Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity.Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |