| Gene Name |
PCDHGC3 |
| Synonyms |
PC-43；PC43；PCDH-GAMMA-C3；PCDH2 |
| English Name |
Recombinant human PCDHGC3 protein |
| Full Name |
protocadherin gamma subfamily C，3 |
| Chinese Name |
原钙粘蛋白γ亚家族C,3 |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
Q9UN70 |
| Gene ID |
5098 |
| Reactivity |
Human (Gorilla) |
| Molecular Weight |
7kDa |
| Interval Range |
1-61aa |
| Background |
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five.These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression.The gamma gene cluster includes 22 genes divided into 3 subfamilies.Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes.The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster.Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region.The constant region exons encode the common cytoplasmic region.These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain.Alternative splicing has been described for the gamma cluster genes. |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
No activity experimental data, to be verified. |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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