English Name |
Anti-NF-H/NF200 Monoclonal Antibody |
Chinese Name |
高分子量神经丝蛋白抗体 |
Host |
Mouse |
Clone Type |
Monoclonal Antibody |
Subtype |
IgG2a |
Dilution Ratio |
WB 1:5000-50000. IHC 1:4000-16000. IF 1:20-200. |
Target |
NF-H/NF200 |
Synonyms |
Neurofilament 200, 200 kDa neurofilament protein, 200 kD Neurofilament Heavy, NEFH, NEFH, NF200, NF-200, Neurofilament H, Neurofilament heavy polypeptide 200kD, Neurofilament heavy polypeptide 200kDa, Neurofilament heavy polypeptide, Neurofilament triplet H protein, Neurofilament triplet H protein, Hypophosphorylated Neurofilament H, NF H, NFH, NFH_HUMAN, KIAA0845 |
Background |
NEFH, also named as KIAA0845 and NFH, Belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody recognize NEFH only. |
Swiss Prot |
P12036 |
Gene ID |
4744 |
Subcellular Location |
Cell projection Cytoplasm Cytoskeleton Intermediate filament |
Immunogen |
Recombinant protein of human NF200 |
Public Immunogen Range |
1-214aa |
Calculated MW |
112Da |
Purification Method |
Protein A purification |
Storage Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Pig Rat Mouse Human |
Application |
ELISA FCM IF IHC WB |