Anti-FCGR3A Polyclonal Antibody
Cat.No:K115467P-Cy7 Solarbio
Reactivity:Human;Mouse;Rat,Rat,Human,Mouse
Application:Cy7
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:2214
Host:Rabbit
Qty:
Size:
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My CartReactivity:Human;Mouse;Rat,Rat,Human,Mouse
Application:Cy7
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:2214
Host:Rabbit
Qty:
Size:
Reactivity | Human;Mouse;Rat,Rat,Human,Mouse |
Background | This gene encodes a receptor for the Fc portion of immunoglobulin G,and it is involved in the removal of antigen-antibody complexes from the circulation,as well as other responses,including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide,whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20,and have been linked to susceptibility to recurrent viral infections,susceptibility to systemic lupus erythematosus,and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Subtype | IgG |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Host | Rabbit |
Application | IHC |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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