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My Cart> Antibodies > Primary Antibodies > Anti-MLLT6 Polyclonal AntibodySAlexa Fluor 488Reactivity：Human
Application：SAlexa Fluor 488
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：4302
Purity：MLLT6
Qty：
Size：
| Reactivity | Human |
| Background | The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10% of patients with acute lymphoblastic leukemia (ALL) and 5% of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. The gene encoding MLLT6， also known as mixed-lineage leukemia translocated to 6 or AF17， is located on chromosome 17q12 and encodes a 1093 amino acid protein that is thought to be involved in the translocations on chromosome 11q23. Localized to the nucleus， MLLT6 contains a leucine-zipper dimerization motif located 3-prime of the fusion point and a cysteine-rich domain at the C-terminus. MLLT6 is thought to play a role in ALL by repressing the activity of the truncated ALL1 protein. |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Application | WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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