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My Cart> Antibodies > Primary Antibodies > Anti-LFNG Polyclonal AntibodySAlexa Fluor 488Reactivity：Rat,Mouse,Human
Application：SAlexa Fluor 488
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：3955
Purity：LFNG
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| Reactivity | Rat,Mouse,Human |
| Background | This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family， which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes， encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases， these proteins have a fucose-specific beta-1，3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch， which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
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