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My Cart> Antibodies > Primary Antibodies > Anti-APLN Polyclonal AntibodySAlexa Fluor 488Reactivity：Human,Mouse,Rat
Application：SAlexa Fluor 488
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：8862
Purity：APLN
Qty：
Size：
| Reactivity | Human,Mouse,Rat |
| Background | Endogenous ligand for the apelin receptor (APLNR) (PubMed:10525157).Drives internalization of the apelin receptor (By similarity).Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR (By similarity).Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity).Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (By similarity).Plays a role in early coronary blood vessels formation (By similarity).Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity).May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (By similarity). |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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