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My Cart> Antibodies > Primary Antibodies > Anti-PCBP2 Polyclonal AntibodySAlexa Fluor 555Reactivity：Human,Mouse
Application：SAlexa Fluor 555
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5094
Purity：PCBP2
Qty：
Size：
| Reactivity | Human,Mouse |
| Background | The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK， it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1， this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES， promoting poliovirus RNA replication by binding to its 5’-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA， human papillomavirus type 16 L2 mRNA， and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1， an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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