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My CartReactivity：Mouse
Application：Cy5
Clone Type：Monoclonal Antibody
Storage：Store at 2-8℃ in dark.Do not freeze.
Gene ID：12525
Purity：CD8a(AF488)
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| Reactivity | Mouse |
| Background | CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains.It can be present as a homodimer of CD8 or as a heterodimer of CD8 and CD8 (PMID: 3264320;8253791).CD8 is found on most thymocytes.The majority of class I-restricted T cells express mostly the CD8 heterodimer while CD8 homodimers alone have been found on some gut intraepithelial T cells on some T cell receptor (TCR) T cells and on NK cells (PMID: 2111591;1831127;8420975).CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079).During T cell development CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). |
| Subtype | IgG2a κ |
| Storage | Store at 2-8℃ in dark.Do not freeze. |
| Application | IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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