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My Cart> Antibodies > Primary Antibodies > Anti-Phospho-AKT(Ser473) Monoclonal AntibodyRBITCClone Type：Monoclonal Antibody
Storage：Store at -20℃.Avoid freeze/thaw cycles.
Gene ID：207
Purity：Phospho-AKT(Ser473)
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| Background | Acts as a regulator of mitochondrial calcium uptake by mediating phosphorylation of MICU1 in the mitochondrial intermembrane space， impairing MICU1 maturation (PubMed:30504268).Acts as an inhibitor of tRNA methylation by mediating phosphorylation of the N-terminus of METTL1， thereby inhibiting METTL1 methyltransferase activity (PubMed:15861136).In response to LPAR1 receptor pathway activation， phosphorylates Rabin8/RAB3IP which alters its activity and phosphorylates WDR44 which induces WDR44 binding to Rab11， thereby switching Rab11 vesicular function from preciliary trafficking to endocytic recycling (PubMed:31204173). |
| Subtype | IgG1 |
| Storage | Store at -20℃.Avoid freeze/thaw cycles. |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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