Anti-EXD2 Polyclonal Antibody
Cat.No:K115916P-Cy7 Solarbio
Reactivity:Human,Mouse
Application:Cy7
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:55218
Purity:EXD2
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My CartReactivity:Human,Mouse
Application:Cy7
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:55218
Purity:EXD2
Qty:
Size:
Reactivity | Human,Mouse |
Background | Exonuclease that has both 3’-5’ exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor (PubMed:29335528, PubMed:31127291).In presence of Mg2+, only shows 3’-5’ exoribonuclease activity, while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn2+ (PubMed:29335528, PubMed:31127291).Acts as an exoribonuclease in mitochondrion, possibly by regulating ATP production and mitochondrial translation (PubMed:29335528).Also involved in the response to DNA damage (PubMed:26807646, PubMed:31255466).Acts as 3’-5’ exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination (PubMed:20603073, PubMed:26807646).Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3’-5’ exonuclease activity, which efficiently |
Subtype | IgG |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Application | WB IHC |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
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