{{cart_num}}
My CartReactivity：Rat,Mouse,Human
Application：HRP
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5802
Purity：PTPRS
Qty：
Size：
| Reactivity | Rat,Mouse,Human |
| Background | Cell surface receptor that binds to glycosaminoglycans， including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan (PubMed:21454754).Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans， also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development， especially for normal development of the pituitary gland and the olfactory bulb. Functions as tyrosine phosphatase (PubMed:8524829).Mediates dephosphorylation of NTRK1， NTRK2 and NTRK3 (By similarity).Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases (By similarity).Down-regulates TLR9-mediated activation of NF-kappa-B， as well as production of TNF， interferon alpha and interferon beta |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no experimental images.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
